| S | South |
| S-G | Space to Ground |
| S/A | Solar Array |
| S/C | Spacecraft |
| S/C | Sub Contract |
| S/C F&PS | Spacecraft Functional and Performance Specification |
| S/MIME | Secure/Multipurpose Internet Mail Extensions |
| S/NA | System and Network Administrator |
| S/W | Software |
| S&ES | Sensing and Exploration Systems |
| S&MA | Safety & Mission Assurance |
| SA | Science Algorithm |
| SA | Security Assessment |
| SA | Software Assurance |
| SA | Solar Array |
| SA | Submission Agreements |
| SA | System Administrator |
| SAB | Satellite Analysis Branch |
| SAD | Solar Array Drive |
| SADA | Solar Array Drive Assembly |
| SADE | Solar Array Drive Electronics |
| SADM | Solar Array Deployment Mechanism |
| SADT | Structured Analysis and Design Technique |
| SAIC | Science Applications International Corporation |
| SAISO | Senior Agency Information Security Officer |
| SALT | S-405 ArcJet Life Test |
| SAM | Supplier Agreement Management |
| SAM | Systems Assurance Manager |
| SAMI | Sources and Methods Information |
| SAML | Security Assertion Markup Language |
| SAN | Storage Area Network |
| SAO | Systems Assurance Office |
| SAO | Systems Acquisition Office |
| SAP | Security Accreditation Package |
| SAP | Security Assessment Plan |
| SAP | Software Assurance Plan |
| SAP | Systems Applications and Products |
| SAPR | Simulator Anomaly Problem Report |
| SAPR | Software Anomaly Problem Report |
| SAR | Safety Assessment Report |
| SAR | Search And Rescue |
| SAR | System Acceptance Review |
| SARB | Surface and Atmospheric Radiation Budget, a component of CERES |
| SARSAT | Search and Rescue Satellite Aided Tracking |
| SAS | Solar Array Shunt |
| SASC | Solar Array Simulation Console |
| SAST | Simulated Antenna System Terminal |
| SAST | Spacecraft All-Software Testbed |
| Sat | Satellite |
| SAT | Site Acceptance Test |
| SATA | Serial Advanced Technology Attachment |
| SATB | Satellite Algorithm Test Bed |
| SATCON | Satellite Controller |
| SATERN | System for Administration, Training and Educational Resources (NASA) |
| SATOPS | Satellite Operations |
| SATS | Solar Array Telemetry Simulator |
| SatSim | Satellite Simulator |
| SAWA | Solar Array Wing Assembly |
| SB | Scientific Boundary |
| SBA | Service Based Architecture |
| SBB | Space Support Building (LM-KO) |
| SBC | Single Board Computer |
| SBCRB | Schedule Baseline Change Request Board |
| SBIR | Small Business Innovation Research |
| SBIRS | Space-Based Infrared System |
| SBT | S-Band Transponder |
| SBT | Space-Based Transmitter |
| SBU | Sensitive But Unclassified |
| SC | Spacecraft |
| SCA | Security Control Assessor |
| SCADA | Supervisory Control and Data Acquisition |
| SCAG | Snow Cover and Grain size |
| SCAMPI | Standard CMMI Appraisal Method for Process Improvement |
| SCaMPR | Self-Calibrating Multivariate Precipitation Retrieval |
| SCAP | Security Content Automation Protocol |
| SCBA | Self-Contained Breathing Apparatus |
| SCCB | Software Configuration Control Board |
| SCD | Source Control Drawing |
| SCEP | Simple Certificate Enrollment Protocol |
| SCF | Sun-Pointing Platform (SPP) Coordinate Frame |
| SCFPS | Spacecraft Functional and Performance Specification |
| SCI | Scalable Coherent Interface |
| SCID | Spacecraft Identifier |
| SCM | Software Configuration Management |
| SCMAR | Spacecraft Mission Assurance Requirements |
| SCMGT | Security and Compliance Management |
| S-CMI | Sectorized Cloud and Moisture Imagery |
| SCMP | Subcontract Management Plan |
| SCN | Spacecraft Navigation |
| SCOUTS | Spacecraft Checkout Universal Test System |
| SCP | Stored Command Processing |
| SCR | Service Component Repository |
| SCR | System Concept Review |
| SCSB | Satellite Climate Studies Branch |
| SCMI | Sectorized Cloud and Moisture Imagery |
| SCT | Solar Calibration Target |
| SCTS | Spacecraft Command and Telemetry Simulator |
| SCTV | Spacecraft Thermal Vacuum |
| SCU-R | System Communications Unit - Replacement |
| SD | Sensor Data |
| SD | System Design |
| SDC | Software Development Course |
| SDD | Software Design Document |
| SDEB | Science and Demonstration Executive Board |
| SDF | Software Development Folder |
| SDK | Software Development Kit |
| SDL | Software Development Library |
| SDLC | Software Development Life Cycle |
| SDLC | System Development Life Cycle |
| SDM | Scalable Data Management |
| SDM | Structured Design Methodology |
| SDO | Solar Dynamics Observatory |
| SDO/AIA | SDO/ Atmospheric Imaging Assembly |
| SDO/EVE | SDO/ Extreme Ultraviolet Variability Experiment |
| SDP | Safety Data Package |
| SDP | Software Development Plan |
| SDR | Sensor Data Record |
| SDR | System Definition Review |
| SDR | System Design Review |
| SDRAM | Synchronous Dynamic Random Access Memory |
| SDRL | Subcontractor Data Requirement List |
| SDRL | Supplier Data Requirement List |
| SDRWG | SE and Development Risk Working Group |
| SDS | System Design Specification |
| SDT | Subjective Dvorak Technique |
| SDVE | Software Development and Validation Environment |
| SE | Systems Engineer |
| SE | Systems Engineering |
| SEA | Systems Engineering Analysis |
| SEB | Sensor Electronics Box |
| SEB | Source Evaluation Board |
| SEB | SUVI Electronics Box |
| SEBN | Surface Energy Balance Network |
| SEC | Security |
| SEC | Space Environment Center (NOAA) |
| SECA | SEISS EHIS L1B Calibration Algorithm |
| SECO | Safety and Environmental Compliance Office |
| SECO | Second Engine Cutoff |
| SEE | Single-Event Effect |
| SEE | Software Engineering Environment |
| SeeBor | Former name for U. Wisconsin Baseline fit surface emissivity database retrieved from MODIS observations |
| SE&I | Systems Engineering and Integration |
| SEER/SEM | System Evaluation and Estimation of Resources/Software Estimating Model |
| SEGA | Sun-Pointing Platform (SPP) Elevation Gimbal Assembly |
| SEI | Software Engineering Institute |
| SEISS | Space Environment In-Situ Suite |
| SEIT | Systems Engineering, Integration & Test |
| SEL | single event latch-up |
| SELTS | Self-Test Software |
| SEM | Software Engineering Model |
| SEM | Space Environment Monitor |
| SEMP | Systems Engineering Management Plan |
| SensorML | Sensor Markup Language |
| SEP | Solar Energetic Particle |
| SEPG | Software Engineering Process Group |
| SEPT | System Functional and Performance Test |
| SET | Single Event Transient |
| SET | Systems Engineering Team |
| SETA | System Engineering and Technical Assistance |
| SEU | Single Event Upset |
| SEVIRI | Spinning Enhanced Visible and Infrared Imager |
| SEWG | Systems Engineering Working Group |
| SFC | Earth Surface |
| SFCG | Space Frequency Coordination Group |
| SFG | System Focus Group |
| SFIA | Space Flight Independent Assurance (KSC) |
| SFP | Small Form-factor Pluggable |
| SFP | Sure-Fire Panel |
| SFT | Short Functional Test |
| SFT | System Functional Test |
| SFTP | Secure File Transfer Protocol |
| SG | Steering Group |
| SG-ICD | Space to Ground Interface Control Document |
| SGC | Space to Ground Communications |
| SGCI | Space to Ground Communications Interface |
| SGE | Solar array Gimbal Electronics |
| SGE | Sun Grid Engine |
| SGIS | Spacecraft General Interface Specification |
| SCIWG | Space-Ground Interface Working Group |
| SGLS | Space-Ground Link System |
| SGLT | Space-Ground Link Terminal |
| SGP | Southern Great Plains |
| SGPS | Solar and Galactic Proton Sensor (SEISS) |
| SGPS-CART | Southern Great Plains Cloud and Radiation Testbed |
| SGS | Svalbard Ground Station |
| SHA | Secure Hashing Algorithm |
| SHCM | Software Hazard Criticality Matrix |
| S-HIS | Scanning High-Resolution Interferometer Sounder |
| SHM | Safe Hold Mode |
| SHS | Secure Hash Standard |
| SHyMet | Satellite Hydrology and Meteorology |
| SI | Scaled Integer |
| SI | Showalter Index |
| SI | System Integration |
| SI | International System of Units (Systeme Internationale) |
| SI | System and Information Integrity |
| SIA | Security Impact Analysis |
| SIC | Sea Ice Concentration |
| SiC | Silicon Carbide |
| SIEM | Security Information and Event Manager |
| SIF | Spacecraft Interface |
| SIFC | Serial Interface Card |
| SIGMET | Significant Meteorological Information |
| SIIS | Spacecraft to Instrument Interface Simulator |
| SIM | Security Information Management |
| SIM | Spacecraft Interface Module |
| SINDA | System Improved Numerical Differencing Analyzer |
| SIP | System Integration Plan |
| SIQT | Software Item Qualification Test |
| SIQT | Software Integration and Qualification Test |
| SIR | Segment Integration Review (Ground Segment) |
| SIR | System Integration Review (Ground Segment) |
| SIRCUS | Spectral Irradiance and Radiance Responsivity Calibrations using Uniform Sources |
| SIRD | System Interface Requirements Document |
| SIS | Solar Imaging Suite |
| SIS | System Interface Specification |
| SISSL | Sun Industry Standards Source License |
| SIST | Solar-Infrared Split-Window Technique |
| SIT | Sea Ice Temperature |
| SIT | Select-In Test |
| SI&T | Site Integration and Test |
| SIU | Sun-pointing system Interface Unit |
| SK | Station Keeping |
| SKMP | System Key Management Plan |
| SL-GMS | Sherrill-Lubinski Graphical Modeling System |
| SLA | Service-Level Agreement |
| SLA | Source Logical Address |
| SLA | SpaceWire Logical Address |
| SLC | Space Launch Complex |
| SLCC | Satellite Launch Commit Criteria |
| SLCC | SW logical lines of code |
| SLE | Space Link Extension |
| SLFM | System Level Fault Management |
| SLI | Second Level Integration |
| SLIM | Software Lifecycle Management |
| SLOC | Source Lines Of Code |
| SLW | Super-cooled Liquid Water |
| SM | Structural Model |
| SM | Suspended Matter |
| SM | System Module |
| SMA | Safety and Mission Assurance |
| SMA | Shape Memory Alloy |
| SMA | |
| SMA | Switch Matrix Assembly |
| SMAL | Software Mission Assurance Lead |
| SMAOD | Suspended Matter, Aerosol Optical Depth |
| SMAP | Safety and Mission Assurance Plan |
| SMAR | Safety and Mission Assurance Readiness Review |
| SMAR | Subcontract Mission Assurance Requirements |
| SMD | Science Mission Directorate (NASA) |
| SMDAA | Science Mission Directorate Associate Administrator (NASA) |
| SMDP | Software Management and Development Plan |
| SME | Subject Matter Expert |
| SMG | Spaceflight Meteorology Group |
| SMHCA | SEISS MPS-Hi L1 Calibration Algorithm |
| SMHCL | SEISS MPS-LO L1 Calibration Algorithm |
| SMO | Systems Management Office |
| SMP | Schedule Management Plan |
| SMP | Software Management Plan |
| SMP | Symmetric Multi-Processing |
| SMPC | System Module Power Console |
| SMR | Source Maintainability, and Recovery Code |
| SMRT | Senior Management Review Team |
| SMS | Session Management Service |
| SMSR | Safety and Mission Success Review |
| SMT | Senior Management Team |
| SMT | Subcontract Management Team |
| SMT | Surface Mount Technology |
| SMTL | Special Mission Time Line |
| SMTP | Simple Mail Transfer Protocol |
| SN | Serial Number |
| SN | Space Network |
| SNAC | Systems and Network Attack Center |
| SNI | Spacecraft Navigation Integration |
| SNM | Spacecraft Navigation Manager |
| SNMP | Simple Network Management Protocol |
| SNODAS | Snow Data Assimilation System (NOHRSC) |
| SNOTEL | Snow Telemetry network (Natural Resources Conservation Service) |
| SNR | Signal-to-Noise Ratio |
| SO | Staff Office |
| SO | System Owner |
| SOA | Service-Oriented Architecture |
| SOC | Science Operations Center |
| SOC | Security Operations Center |
| SOCC | Satellite Operations Control Center |
| SODAR | Sonic Detection and Ranging |
| SOE | Sequence Of Events |
| SOE | Standards Of Excellence |
| SOGUD | Satellite Operations Graphical User Display |
| SOH | Satellite Operations Handbook |
| SOH | State Of Health |
| SOHO | Satellite and Heliospheric Observatory |
| SOHO/EIT | Solar and Heliospheric Observatory/Extreme ultraviolet Imaging Telescope |
| SOI | Successive Order of Integration |
| SOMD | Space Operations Mission Directorate |
| SoNAS | Sale out Network Attached Storage |
| SONG | Schedule Oversight and Negotiation Group |
| SOO | Science and Operations Officer (National Weather Service) |
| SOP | Standard Operating Procedure |
| SOPS | Satellite Operations |
| SOS | Science On a Sphere (NOAA) |
| SOW | Statement of Work |
| SOZ | Satellite Operations Zone |
| SOZDMZ | Satellite Operations Zone De-Militarized Zone |
| SOZnet | Satellite Operations Zone Network |
| SP | Special Publication |
| SPARC | Scalable Processor Architecture |
| SPC | Storm Prediction Center |
| SPD | System Program Director |
| SPE | Solar Proton Event |
| SPF | Single Point Failure |
| SPG | Single Point Ground |
| SPI | Schedule Performance Index |
| SPIB | Software Process Improvement Board |
| SPLF | Symmetrical Prominent Low Frequencies |
| SPM | Subcontract Project Manager |
| SPoRT | Short-term Prediction Research and Transition Center (NASA) |
| SPOT | System Performance and Operations Test |
| SPP | Sun-Pointing Platform |
| SPR | Software Problem Report |
| SPR | Solar Radiation Pressure |
| SPRU | Scalable Power Regulation Unit |
| SPS | Samples Per Second |
| SPS | Standby Policy Server |
| SPS | Sun Pointing System/Subsystem |
| SPSRB | Satellite Products and Services Review Board (NESDIS) |
| SPVP | System Performance Verification Plan |
| SpW | SpaceWire |
| SpWRC | SpaceWire Router Card |
| SQ | Software Quality |
| SQ | Supplier Quote |
| SQA | Software Quality Assurance |
| SQAP | Software Quality Assurance Plan |
| SQE | Software Quality Engineer |
| SQL | Structured Query Language |
| SQPSK | Staggered Quadrature Phase Shift Keying |
| SQR | Software Qualification Review |
| SR-IOV | Single Root – IO Virtualization |
| SR | Service Request |
| SR | Status Review |
| SR | System Requirement |
| SRA | Schedule Risk Assessment |
| SRAM | Static Random Access Memory |
| SRAS | Secure Remote Access Server |
| SRB | Schedule Review Board |
| SRB | Shortwave Radiation Budget |
| SRB | Software Review Board |
| SRB | Solid Rocket Booser |
| SRB | Standing Review Board |
| SRD | System Requirements Document |
| SRF | Spectral Response Function |
| SRIF | Square Root Information Filter |
| SRND | Solution Reference Network Design |
| SRP | Solar Radiation Pressure |
| SRP | System Review Plan |
| SRR | Security Readiness Review |
| SRR | System Readiness Review |
| SRR | System Requirements Review |
| SRRC | Square Root Raised Cosine Filter |
| SRS | Shock Response Spectra |
| SRS | Software Requirements Specification |
| SRS | Supplier Rating System |
| SRT | System Review Team |
| SS | Skill Score |
| SS | Space Segment |
| SSA | Source Selection Authority |
| SSAI | Satellite Systems and Applications, Inc. |
| SSAS | Ship Security Alerting System |
| SSB | Space Support Building |
| SSCA | SEISS SGPS L1 Calibration Algorithm |
| SSD | Satellite Services Division (NESDIS) |
| SSD | SCADA Security Domain |
| SSD | Solid State Detectors |
| SSD | Space Systems Division |
| SSD | Sum of Squared Differences |
| SSE | Systems Safety Engineering |
| SSE | System Security Engineering |
| SSE | System Support Engineering |
| SSEC | Space Science Engineering Center (University of Wisconsin-Madison) |
| SSGS | Spacecraft Support Ground System (GOES-N/O/P) |
| SSH | Secure Socket Shell |
| SSHD | Secure Shell Daemon |
| SSIRU | Scalable Space Inertial Reference Unit |
| SSL | Secure Sockets Layer |
| SSL | Space Simulation Lab |
| SSL | Space Systems Lab |
| SS&MA | System Safety and Mission Assurance |
| SSM/I | Special Sensor Microwave/Imager |
| SSMIS | Special Sensor Microwave Imager Sounder |
| SSO | Single Sign On |
| SSO | Source Selection Official |
| SSO | Special Security Office |
| SSP | Sub Satellite Point |
| SSP | System Security Plan |
| SSPA | Solid State Power Amplifiers |
| SSPO | Systems Safety Program Office |
| SSPP | System Safety Program Plan |
| SSR | Satellite Storage Review |
| SSR | Swath to Swath Registration |
| SSRD | Split Spool Release Device |
| SSS | Sub System Specification |
| SST | Sea Surface Temperature |
| SSTC | Sea Surface Temperature Compositing Algorithm |
| ST&C | Satellite Telemetry and Command Handbook |
| ST&E | Security Test and Evaluation |
| STA | Star Tracker Assembly |
| STAR | Center for Satellite Applications and Research |
| STD | Standard |
| STE | System Test Equipment |
| STEM | Science, Technology, Engineering, and Mathematics |
| STEREO | Solar Terrestrial Relations Observatory |
| STI | Scientific and Technical Information |
| STIG | Security Technical Implementation Guide |
| STIWG | Satellite Telemetry Interagency Working Grou |
| STK | Satellite Tool Kit |
| STM | Safe To Mate |
| STNI | Segment Test Name Identifier |
| STOL | Satellite Test and Operations Language |
| STOP | Structural, Thermal, Optical, Performance |
| STORMnet | NSSTC Severe Thunderstorm Observations and Research Meteorological network |
| STP | Software Test Plan |
| STR | Software Test Report |
| STRD | System Test Requirements Document |
| STS | Short Term Storage |
| STS | Space Transportation System |
| STS | SUVI Telescope System |
| STT | Small Tactical Terminal |
| SU | Sensor Unit (GLM) |
| SU | Start Up |
| SUE | Sensor Unit Electronics |
| SUM | Software User Manual |
| SURF | Synchrotron Ultraviolet Radiation Facility |
| SURFRAD | SURFace RADiation Budget |
| SURG | Stakeholder and User Readiness for GOES-R |
| SUROM | Startup Read Only Memory |
| SUST | Sustainment Engineering |
| SUVI | Solar Ultraviolet Imager |
| SUVI GT | SUVI Guide Telescope |
| SV | Schedule Variance |
| SV | Space Vehicle |
| SVU | SAP Version Update |
| SVVP | Software Verification and Validation Plan |
| S/W | Software |
| SW | Short-Wave |
| SW/M | Severe Weather/Mesoscale |
| SW/T | Software Integration and Test |
| SWAMP | Software Acquisition Management Plan |
| SWAROM | SpaceWire ASIC Read-Only Memory |
| SWAT | Software Acceptance Test |
| SWCCB | Software Configuration Control Board |
| SWCDR | Software Critical Design Review |
| SWCM | Software Configuration Management |
| SWDD | Software Detailed Design |
| SWE | Software Engineering |
| SWEHB | Software Engineering Handbook (NASA) |
| SWEWG | Software Engineering Working Group |
| SWFO | Space Weather Follow-on Program |
| SWG | Safety Working Group |
| SWG | Security Working Group |
| SWH | System Warrant Holder |
| SWIR | Short Wave IR |
| SWORD | SpaceWire Operations Run or Discontinue |
| SWPC | Space Weather Prediction Center (formerly known as Space Environment Center - SEC) |
| SWPDR | Software Preliminary Design Review |
| SWQR | Software Qualification Review |
| SWRA | Software Requirements Analysis |
| SWRC | Space Wire Router Card |
| SWRR | Software Requirements Review |
| SWRS | Software Requirement Specification |
| SWS | Solar Wing Subsystem |
| SWTRR | Flight Software Test Readiness Review |
| SWUPD | Software Update Service |
| SXI | Solar X-Ray Imager (GOES-N/O/P) |
| SYSDBA | System Data Base Administrator |
| SYSOPR | System Operator |
| SZA | Solar Zenith Angle |